Tetrabenazine CAS NO.58-46-8

1. Introduction of (Tetrabenazine CAS No.:58-46-8)
With the CAS registry number of 58-46-8, tetrabenazine is also known as 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3S,11bS)-. This chemical's molecular formula is C₁₉H₂₇NO₃ and molecular weight is 317.42. What's more, both its IUPAC name and systematic name are the same which is called (3S,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. Tetrabenazine is a drug for the symptomatic treatment of hyperkinetic movement disorder.

2. Properties of (Tetrabenazine CAS No.:58-46-8)
Density: 1.127 g/cm³
Melting Point: 128-130 °C
Boiling Point: 448.941 °C at 760 mmHg
Flash Point: 225.311 °C
Appearance: white to off-white solid

3. Structure Descriptors of (Tetrabenazine CAS No.:58-46-8)
You can still convert the following datas into molecular structure:
(1) SMILES: O=C3[C@@H](CC(C)C)CN2[C@H](c1c(cc(OC)c(OC)c1)CC2)C3
(2) InChI: InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m0/s1
(3) InChIKey: MKJIEFSOBYUXJB-HOCLYGCPSA-N

4. Toxicity of (Tetrabenazine CAS No.:58-46-8)

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	250mg/kg (250mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LD50	intravenous	150mg/kg (150mg/kg)		Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse	LD50	oral	550mg/kg (550mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 308, 1972.
mouse	LD50	subcutaneous	400mg/kg (400mg/kg)		"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 308, 1972.

5. Safety Information of (Tetrabenazine CAS No.:58-46-8)
Hazard Symbols: Xn
Risk Codes: 22

6. Other details of (Tetrabenazine CAS No.:58-46-8)
When you are dealing with tetrabenazine, you should be very careful. This chemical may cause damage to health and it is harmful if swallowed.